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Indinavir adverse effects

These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about. Commonly reported side effects of indinavir include: nephrolithiasis and urolithiasis. See below for a comprehensive list of adverse effects HIV is the virus that causes acquired immune deficiency syndrome (AIDS). Indinavir will not cure or prevent HIV infection or AIDS. It helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay problems that are usually related to AIDS or HIV disease from occurring

Indinavir may cause side effects. Tell your doctor if this symptom is severe or does not go away: change in sense of taste Indinavir may cause side effects Indinavir is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. Indinavir is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Indinavir is not a cure for HIV or AIDS. Indinavir may also be used for purposes not listed in this medication guide The most common side effects of indinavir include: Gastrointestinal disturbances (abdominal pain, diarrhea, nausea, vomiting) General malaise and fatigue Nephrolithiasis/urolithiasis (the formation of kidney stones), which sometimes may lead to more severe condition including kidney failur

Indinavir (Crixivan). [No authors listed] PMID: 11708184 [PubMed - indexed for MEDLINE] Publication Types: Newspaper Article; MeSH Terms. Drug Resistance, Microbial/genetics; HIV/drug effects; HIV/genetics; HIV Infections/drug therapy* HIV Protease Inhibitors/administration & dosage; HIV Protease Inhibitors/adverse effects; HIV Protease. The main adverse effects seen with indinavir are nephrolithiasis, unconjugated hyperbilirubinemia without jaundice, abdominal pain, nausea, and dry skin and lips Indinavir increases blood levels of sildenafil (Revatio) and the risk of side effects such as low blood pressure, prolonged erection, and fainting. Is indinavir safe to take if I'm pregnant or breastfeeding? Use of indinavir during pregnancy has not been adequately evaluated. It is not known whether indinavir is excreted in breast milk

Several medications--notably acyclovir, sulfonamides, methotrexate, indinavir, and triamterene--are associated with the production of crystals that are insoluble in human urine. Intratubular precipitation of these crystals can lead to acute renal insufficiency Adverse Effects: The most common adverse effects are nephrolithiasis, asymptomatic hyperbilirubinemia and hepatitis. Nephrolithiasis can be prevented with adequate hydration of at least 1.5 liters of liquids daily. Management of nephrolithiasis may require temporary discontinuation of indinavir for one to three days or permanent discontinuation Indinavir may cause other side effects. Call your doctor if you have any unusual problems while taking this medication. Warnings & Precautions. Before taking indinavir, tell your doctor and pharmacist if you are allergic to indinavir, any other medications, or any of the ingredients in indinavir capsules Consult your doctor or pharmacist for more details.This drug is not recommended for use in children due to an increased risk of serious side effects. How to use Indinavir Capsul

Indinavir (Oral Route) Side Effects - Mayo Clini

  1. List indinavir oral side effects by likelihood and severity ; The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor.
  2. istration with drugs primarily metabolized by CYP3A4 may result in increased plasma concentrations of the other drug, which could increase or prolong its therapeutic and adverse effects. Indinavir is metabolized by CYP3A4
  3. Although indinavir is well tolerated, commonly encountered adverse effects include indirect hyperbilirubinemia (10%) and nephrolithiasis (5%)
  4. Crixivan (indinavir sulfate) is a type of antiviral medication called a protease inhibitor used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). Crixivan is not a cure for HIV or AIDS. What Are Side Effects of Crixivan? Common side effects of Crixivan include
  5. Indinavir may cause side effects. Most side effects from indinavir are manageable, but a few can be serious. Serious side effects of indinavir include kidney problems, hemolytic anemia (rapid.
  6. al pain, nausea, vomiting, and diarrhea occurred in 16.6, 11.7, 8.4, and 3.3%, respectively, and acid regurgitation, anorexia, dyspepsia, increased appetite, and taste perversion occurred in 1.5-2.7% of patients receiving indinavir monotherapy
  7. Adverse reactions led to drug discontinuation in 4 cases. Steady-state pharmacokinetic analysis in 17 patients was consistent with an interaction between nevirapine and indinavir. Nevirapine plasma levels were within the expected range, while indinavir levels were lower than expected

Crixivan (indinavir) is an antiviral medication and protease inhibitor used to treat human immunodeficiency virus (HIV). Common side effects of Crixivan include abdominal pain, weakness, nausea, diarrhea, vomiting, headache, insomnia, abnormal taste sensation, and redistribution or accumulation of body fat. Consult your doctor before taking Crixivan if pregnant or breastfeeding The chance of indinavir's side effects may be raised or how well indinavir works may be lowered. The chance of the other drugs' side effects may also be raised. This may include very bad, life-threatening, or deadly side effects. Check with your doctor and pharmacist to make sure that it is safe for you to take indinavir with all of your other.

These are not all the possible side effects of Crixivan. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. DESCRIPTION. CRIXIVAN® (indinavir sulfate) is an inhibitor of the human immunodeficiency virus protease. CRIXIVAN Capsules. Indinavir has been associated with metabolic abnormalities including hyperglycemia, dyslipIdemia, and abnormalities in fat distribution. It is essential to assess patient motivation and discuss possible side effects and strategies for their management before treatment with indinavir is initiated Indinavir is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. Indinavir is used to treat HIV, the virus that can cause acquired immunodeficiency..

Indinavir Side Effects: Common, Severe, Long Term - Drugs

The risk or severity of adverse effects can be increased when Indinavir is combined with Norepinephrine. Norethisterone: The metabolism of Norethisterone can be decreased when combined with Indinavir. Norfloxacin: The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Indinavir is combined with Norfloxacin. Due to a significant decrease in indinavir exposure, administration of a higher dose of Because of the potential for adverse effects on the newborn, nursing should be discontinued if Megace® ES oral suspension is required. 8.4. Pediatric use

Antiretroviral drugs

The intensity and duration of reported adverse effects were less during the second phase of indinavir. This study shows a large reduction in indinavir concentrations by concomitant St John's wort. These results have important clinical implications for HIV-infected patients receiving these two agents since low plasma concentrations of protease. Bromfenac caused serious hepatotoxicity in only 1 in 20,000 patients taking the drug for longer than 10 days. 1 To reliably detect the toxic effects of a drug with a 1 in 20,000 adverse drug. Indinavir is usually taken every 8 hours around the clock. Take the medicine at the same times each day. Take indinavir with a full glass (8 ounces) of water, skim milk, juice, coffee, or tea. Drink at least 6 glasses of water each day to prevent kidney stones while you are taking indinavir Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 Indinavir is an inhibitor of the cytochrome P450 isoform CYP3A4. Coadministration of CRIXIVAN and drugs primarily metabolized by CYP3A4 may result in increased plasma concentrations of the other drug, which could increase or prolong its therapeutic and adverse effects (see CONTRAINDICATIONS and WARNINGS)

Indinavir is an antiviral drug used in the treatment of human immunodeficiency virus (HIV) infection. This medicine will not cure HIV, but it will decrease the chance of developing acquired immunodeficiency syndrome (AIDS) and other HIV-related illnesses. Transmitting of HIV infection to other people can be prevented by taking this medicine along with practicing safer sex and other lifestyle. Adverse effects associated with zidovudine include bone marrow suppression, nausea and vomiting, fatigue, and headache. Lamivudine and emtricitabine are well tolerated. However, in patients with.

Adverse Effects. Use of protease inhibitors may result to these adverse effects: GI: nausea, vomiting, diarrhea, anorexia, changes in liver function (elevated cholesterol and triglyceride) Skin: rashes, pruritus, Steven Johnson syndrome; Interactions. The following are drug-drug interactions involved in the use of protease inhibitors Indinavir is a type of anti-HIV drug called a protease inhibitor. The most common side effects of indinavir can include nausea, headache, diarrhea, vomiting, and weakness. Indinavir can also cause kidney stones, but drinking a minimum of 1.5 litres of water daily, in addition to your regular intake of other fluids, can help reduce this. Find treatment reviews for Indinavir (IDV) from other patients. Learn from their experiences about effectiveness, side effects and cost Dismiss this notification PatientsLikeMe would like to remind you that your browser is out of date and many features of the website may not function as expected Indinavir is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. Indinavir is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Indinavir is not a cure for HIV or AIDS. Indinavir may also be used for purposes not listed in this.. Side Effects The side effects for ritonavir seem to be the most severe. Nausea, vomiting, and diarrhea are some of them. For indinavir, the side effects are kidney stones, which can cause pain in the back and side. Saquinavir seems to have the least side effects. Nausea, diarrhea, and stomach discomfort occur in very few people. Back to Beginnin

rugs, Mechanism Of Action, Adverse Effects, 2007

Indinavir(Crixivan) generic is a protease inhibitor, prescribed for human immunodeficiency virus (HIV) infection in adults that slow the spread of HIV infection in the body. It works by blocking. Antiretroviral drugs can cause side effects that can be severe enough to make some people stop taking them. But if a person with HIV skips doses of these drugs, the virus can start copying itself. Indinavir exhibits the greatest potential for altering glucose metabolism. Modest effects have been observed with nelfinavir, lopinavir/ritonavir, fosamprenavir, and tipranavir Studies in lactating rats have demonstrated that indinavir is excreted in milk. Although it is not known whether CRIXIVAN is excreted in human milk, there exists the potential for adverse effects from indinavir in nursing infants. Mothers should be instructed to discontinue nursing if they are receiving CRIXIVAN Adverse effects have been reported with all antiretroviral (ARV) drugs and were among the most common reasons for switching or discontinuing therapy, and for medication nonadherence in the earlier era of combination antiretroviral therapy (ART). 1 Fortunately, newer ARV regimens are associated with fewer serious and intolerable adverse effects.

Indinavir: MedlinePlus Drug Informatio

  1. Side effects can play a large role in discouraging adherence to therapy, which may in turn impact the development of drug resistance. Some drugs, notably indinavir (Crixivan) and d4T, have.
  2. Side effects can also occur because of interactions between ART and other medicines that you take. Ziagen), didanosine, indinavir (brand name: Crixivan), lopinavir/ritonavir (brand name.
  3. orchitis. Systemic adverse effects are uncommon but can be severe.21 Miliary tuberculosis is a very rare complication of BCG instillation; anti-tuberculous chemotherapy is an effective treatment.22 Antibiotics Antibacterial colitis and antimicrobial resistance are well known adverse effects of long-term antibacterial prophylaxis
  4. e, ergonovine, ergonovine ergota
  5. al pain, vomiting, insomnia, peripheral neurologic symptoms, dizziness, muscle pain, diarrhea, depression and fever. Bilirubin levels in the blood are normally asymptomatically raised with atazanavir, but can sometimes lead to jaundice
  6. The two-drug combination of efavirenz plus indinavir had fewer adverse effects than the combination of indinavir and two nucleoside reverse-transcriptase inhibitors, and the efficacy of the two.

Indinavir Uses, Side Effects & Warnings - Drugs

  1. to your doctor about possible drug interactions and side effects. If you take any of these medicines together with CRIXIVAN, you may beat increased risk of side effects such as low blood pressure, visual changes, and penile erection lasting more than 4 hours, which have been associated with sildenafil, tadalafil, and vardenafil
  2. Cyclosporine (Gengraf, Neoral, Sandimmune) oral capsule is a prescription medication used to treat rheumatoid arthritis and psoriasis. Learn about side effects, warnings, dosage, and more
  3. Table 20. Common and/or Severe Adverse Effects Associated with Antiretroviral Therapy; Adverse Effect Drug Class; NRTIs NNRTIs PIs INSTIs EIs; Bone Density Effects: TDF: Associated with greater loss of BMD than other NRTIs, especially when given with a PK booster. Osteomalacia may be associated with renal tubulopathy and urine phosphate wasting
  4. Lewi DS, Suleiman JM, Uip DE, et al. Randomized, double-blind trial comparing indinavir alone, zidovudine alone and indinavir plus zidovudine in antiretroviral therapy-naive HIV-infected individuals with CD4 cell counts between 50 and 250/mm 3. Rev Inst Med Trop Sao Paulo. 2000;42:27-36

Indinavir - Wikipedi

Potential indinavir side effects include fever, cough, and nausea. This eMedTV page lists some of the most common side effects of indinavir, as well as less common but potentially serious side effects that require immediate medical attention Because of the potent antiretroviral activity of indinavir 8,12 and the sustained antiretroviral effects of the combination of zidovudine and lamivudine, 1,2 we decided to study regimens designed. Possible side effects from indinavir may include: abdominal pain weakness nausea diarrhea vomiting headache insomnia abnormal taste sensation. Tell your doctor if any of these symptoms are severe or do not go away: changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist) stomach pain nausea. Side Effects. Crixivan has been generally well tolerated in clinical trials. Nephrolithiasis (defined as flank pain, blood in the urine or kidney stones) occurred in approximately 4% of subjects. People who take Crixivan are encouraged to drink at least 48 ounces of water every day to maintain hydration and help avoid nephrolithiasis CRIXIVAN prescription and dosage sizes information for physicians and healthcare professionals. Pharmacology, adverse reactions, warnings and side effects

Medical Pharmacology: Antiviral Drugs

Indinavir (Crixivan)

Indinavir - an overview ScienceDirect Topic

Crixivan (indinavir): Drug Information, Side Effects and

Crystal-induced acute renal failur

The European patient information and detailed Product Information for indinavir are available in PDF format from this linkat the European Medicines Agency (EMA) website. The Patient Information is a simplified summary: what the drug is, why it is used, results from studies and cautions including side effects The development of nephrolithiasis in HIV-infected persons has been classically associated with indinavir use, which is currently not approved below 18 years of age. 10, 11 This adverse event is related to higher plasma concentrations of indinavir and may occur soon after implementing the drug; it has seldom been reported in the pediatric age. Coadministration of Indinavir and drugs primarily metabolized by CYP3A4 may result in increased plasma concentrations of the other drug, which could increase or prolong its therapeutic and adverse effects. Indinavir is metabolized by CYP3A4

Indinavir - Antimicrob

Indinavir: Overview, Uses, Side Effects, Precautions

  1. St. John's wort has a low incidence of side effects compared to prescription antidepressants. An adverse events profile of St. John's wort found that, of 14 controlled clinical trials, seven reported no adverse reactions, two had no information, and five reported a total of seven mild reactions. 4 Adverse effects reported included stomach upset, fatigue, itching, sleep disturbance, and skin rash
  2. Possible increased amiodarone effects (eg, hypotension, bradycardia, cardiac arrhythmias) Inhibition of CYP3A4 by cobicistat. Use with caution; monitor amiodarone adverse effects. Consider obtaining ECG and monitoring amiodarone levels. Antiretroviral (ARV) Dose of ARV. Dose of Amiodarone. Effect on ARV Levels
  3. istered to pregnant women. Indinavir: (Major) Due to the significant decrease in the.
  4. Possible Side Effects. Because Triphala acts as a mild laxative, it may cause gastrointestinal side effects, including gas, stomach upset, cramps, and diarrhea. Depending on the preparation used, side effects like these may occur with even smaller doses
  5. Advair (fluticasone propionate/salmeterol) is a brand-name drug used to treat asthma and COPD. Advair comes in two forms: Advair Diskus and Advair HFA. Learn about side effects, dosage, and more

Indinavir Oral: Uses, Side Effects, Interactions, Pictures

Inhibition of CYP450 3A4 by indinavir: Do not coadminister. Antiretroviral (ARV) Dose of ARV Dose of Pimozide Effect on ARV Levels Effect on Pimozide Levels Potential Clinical Effects Mechanism of Interaction Management; Possible increased risk of quetiapine adverse effects Indinavir is a prescription medicine that is approved for treating HIV and AIDS in adults. This page on the eMedTV site describes the effects of indinavir, explains how the drug works, and lists possible side effects that may occur during treatment FPnotebook.com is a rapid access, point-of-care medical reference for primary care and emergency clinicians. Started in 1995, this collection now contains 6963 interlinked topic pages divided into a tree of 31 specialty books and 737 chapters

PPT - Post-Exposure Prophylaxis an evidence-based review

Common and Rare Side Effects for indinavir ora

Triazolam may increase the risk of serious or life-threatening breathing problems, sedation, or coma if used along with certain medications. Tell your doctor if you are taking or plan to take certain opiate medications for cough such as codeine (in Triacin-C, in Tuzistra XR) or hydrocodone (in Anexsia, in Norco, in Zyfrel) or for pain such as codeine (in Fiorinal), fentanyl (Actiq, Duragesic. Indinavir belongs to a class of drugs known as protease inhibitors. It may be given with ritonavir, another protease inhibitor, to increase (boost) the levels of indinavir. Children may be more sensitive to the side effects of this drug, especially effects on the kidney (such as kidney stones) Other adverse effects are diarrhea, nausea, vomiting, abdominal pain, headache, peripheral neuropathy, abnormal sensations (paresthesias), reduced white blood counts, increased liver enzymes and skin rash. Increased bilirubin is seen with atazanavir and indinavir. Kidney stones and crystaluria are common with indinavir This is not a complete list of estradiol side effects. Ask your doctor or pharmacist for more information. Tell your doctor if you have any side effect that bothers you or that does not go away. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 data of indinavir q8h in both adults and children [7]. This increased AUC may result in a higher incidence of side effects, especially when instructions to increase fluid in-take are not sufficiently followed. This is of major concern since the occurrence of side effects poses a major threat to the adherence, whilst maintenance of adherence was th

Indinavir - Mechanism, Indication, Contraindications

Rupall: Rupatadine belongs to the class of medications called second-generation antihistamines, specifically the class known as histamine receptor antagonists. It works by blocking the action of one of the body's natural chemicals known as histamine. Histamine is responsible for many of the symptoms caused by allergies Some of these side effects can adversely affect your mood and behavior, causing an altered perception of yourself, your environment, or your relationships. Long-term side effects may include: Acute anxiety. Agoraphobia (the fear of open or public spaces) Anhedonia (the inability to feel pleasure) Depression • • • • Adverse effects: Diarrhea, nausea, abdominal discomfort Hyperglycemia, fat redistribution, hyperlipidemia Bleeding episodes in hemophilics 30. Saquinavir (SQV) • Saquinavir is a potent inhibitor of HIV-1 and HIV-2 protease. • It is usually well tolerated and most frequently produces mild gastrointestinal side effects. 31 Indinavir (Crixivan, IDV) Side effects include change in sense of taste, diarrhea, nausea, vomiting, dizziness or drowsiness, general feeling of weakness, headache, stomach pain and trouble sleeping. More serious side effects include kidney stones, changes in body fat, increased bleeding in patients with hemophilia, high sugar and fat levels in.

Chronic Opioid Therapy for Chronic Musculoskeletal Pain

Side Effects of Crixivan (Indinavir Sulfate), Warnings, Use

These are not all the possible side effects of VIAGRA. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Learn more about the possible side effects of VIAGRA Examples of other drugs for HIV infections: nucleoside analogs - didanosine, lamivudine, stavudine, zalcitabine, zidovudine (AZT); protease inhibitors - indinavir, ritonavir, saquinavir. Side Effects: The most common side effects of Efavirenz or Sustiva have been dizziness, headache, insomnia, inability to concentrate, and rash Crixivan: Indinavir belongs to the class of antiretroviral medications called protease inhibitors. It is used in combination with other HIV medications to treat the infection caused by the human immunodeficiency virus (HIV). HIV is the virus responsible for acquired immune deficiency syndrome (AIDS). HIV infection destroys CD4 (T) cells, which are important to the immune system

An Overview of Crixivan (Indinavir

Purpose of review . To review evidence relating to the strength of associations that have appeared in largely observational studies, between high-dose or long-term use of proton pump inhibitor drugs and certain possibly attributable side-effects, which emerge from studies confounded by other variables U.S. National Library of Medicine. U.S. National Library of Medicine. REPORT ADVERSE EVENTS | Recall Analysis of long-term data from Study 006 (median follow-up 180 weeks, 102 weeks, and 76 weeks for patients treated with Efavirenz + zidovudine + lamivudine, Efavirenz + indinavir, and indinavir + zidovudine + lamivudine, respectively) showed that, beyond 24 weeks of therapy, the incidences of new-onset nervous system symptoms among Efavirenz.

Indinavir sulfate C36H49N5O8S - PubChe

VIAGRA can cause serious side effects. Rarely reported side effects include: an erection that will not go away (priapism). If you have an erection that lasts more than 4 hours, get medical help right away. If it is not treated right away, priapism can permanently damage your penis; sudden vision loss in one or both eyes Daclatasvir may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: headache. diarrhea. Some side effects can be serious. If you are also taking amiodarone and you experience any of these symptoms or those in the IMPORTANT WARNING section, call your doctor immediately

Core Concepts - Adverse Effects of Antiretroviral